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Item number680327
Molecular weight359,48 g/mol
Quantity 10 mg
Storage conditions20 °C
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Safety Data Sheetin accordance with 29 CFR § 1910.1200 (OSHA HCS)
Issuedate February 18, 2020
Product name:Isofetamid
Catalog No.:680327
Relevant identified uses of the substance or mixtureIdentified: Laboratory chemical
uses: R&D
Uses advised against:HPC Standards Inc
1170 Howell Mill Road, Suite 300
Atlanta, GA 30318

Tel. +1 (678) 244-1536
Fax. +1 (404) 586-6820
HAZARDS IDENTIFICATIONPhysical hazards Not classified.
Health hazards Not classified.
Hazardous to the aquatic environment, acute Category 2
Environmental hazards
Hazardous to the aquatic environment, Category 2
long-term hazard
OSHA defined hazards Not classified.
Label elementsLabelling according Regulation (EC) No 1272/2008 [CLP]
PictogramGHS08 silhouete
Signal word Warning
Hazard statement Toxic to aquatic life. Toxic to aquatic life with long lasting effects.
Precautionary statement
Prevention Avoid release to the environment.
Response Collect spillage.
Storage Store away from incompatible materials.
Disposal Dispose of contents/container in accordance with local/regional/national/international regulations.
Hazard(s) not otherwise
classified (HNOC)
None known.
Supplemental information None.
Chemical name
Common name and synonyms
3- methyl- N- (2- methyl- 1- (2- methyl- 4- (propan-
2- yloxy) phenyl) - 1- oxopropan- 2- yl) thiophene-
2- carboxamide
CAS number
Molecular Weight (g/mol)359.48
Move to fresh air. Call a physician if symptoms develop or persist.
Skin contact
Wash off with soap and water. Get medical attention if irritation develops and persists.
Eye contact
Rinse with water. Get medical attention if irritation develops and persists.
Rinse mouth. Get medical attention if symptoms occur.
Most important symptoms/effects, acute and delayed
Direct contact with eyes may cause temporary irritation.
Indication of immediate medical attention and special treatment needed
Treat symptomatically.
General information
Ensure that medical personnel are aware of the material(s) involved, and take precautions to
protect themselves.
FIRE-FIGHTING MEASURESSuitable extinguishing media
Water fog. Foam. Dry chemical powder. Carbon dioxide (CO2).
Unsuitable extinguishing media
Do not use water jet as an extinguisher, as this will spread the fire.
Specific hazards arising from the chemical
During fire, gases hazardous to health may be formed.
Special protective equipment and precautions for firefighters
Self-contained breathing apparatus and full protective clothing must be worn in case of fire.
Fire fighting equipment/instructions
Use water spray to cool unopened containers.
Specific methods
Use standard firefighting procedures and consider the hazards of other involved materials.
General fire hazards
No unusual fire or explosion hazards noted.
ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency procedures
Mount respiratory protective device.
Avoid formation of dust.
· 6.2 Environmental precautions:
Inform respective authorities in case of seepage into water course or sewage system.
Do not allow to enter sewers/ surface or ground water.
· 6.3 Methods and material for containment and cleaning up:
Dispose of contaminated material as waste according to item 13.
Ensure adequate ventilation.
· 6.4 Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
HANDLING AND STORAGEPrecautions for safe handling
Provide adequate ventilation. Wear appropriate personal protective equipment. Avoid release to
the environment. Observe good industrial hygiene practices.
Conditions for safe storage, including any incompatibilities
Store in original tightly closed container. Store away from incompatible materials (see Section 10
of the SDS).
7.2. Bedingungen zur sicheren Lagerung unter Berücksichtigung von Unverträglichkeiten
Im fest verschlossenen Originalbehälter lagern. Von unverträglichen Stoffen fernhalten (Siehe
Abschnitt 10 des MSDB).
7.3. Spezifische Endanwendungen
Steht nicht zur Verfügung.
No exposure limits noted for ingredient(s).
Biological limit values
No biological exposure limits noted for the ingredient(s).
Appropriate engineering controls
Good general ventilation (typically 10 air changes per hour) should be used. Ventilation rates
should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation,
or other engineering controls to maintain airborne levels below recommended exposure limits. If
exposure limits have not been established, maintain airborne levels to an acceptable level.
Individual protection measures, such as personal protective equipment
Eye/face protection
Wear safety glasses with side shields (or goggles).
Skin protection
Hand protection
Wear appropriate chemical resistant gloves. Suitable gloves can be recommended by the glove
Wear suitable protective clothing.
Respiratory protection
In case of insufficient ventilation, wear suitable respiratory equipment.
Thermal hazards
Wear appropriate thermal protective clothing, when necessary.
General hygiene considerations
Always observe good personal hygiene measures, such as washing after handling the material
and before eating, drinking, and/or smoking. Routinely wash work clothing and protective
equipment to remove contaminants.
Physical state Solid.
Form Solid.
Color White to light brown
Odor Not available.
Odor threshold Not available.
pH Not available.
Melting point/freezing point 218.3 °F (103.5 °C)
Initial boiling point and boiling
Decomposes before boiling.
Flash point Not available.
Flash point Not available.
Evaporation rate Not available.
Flammability (solid, gas) Not available.
Upper/lower flammability or explosive limits
Flammability limit - lower(%) Not available.
Flammability limit - upper(%) Not available.
Explosive limit - lower (%) Not available.
Explosive limit - upper (%) Not available.
Vapor pressure 0.0004 mPa at 25 °C
Vapor density Not available.
Relative density Not available.
Solubility (water) 5.33 mg/l at 20 °C
Partition coefficient (n-octanol/water) Not available.
Auto-ignition temperature Not available.
Decomposition temperature 348.8 °F (176 °C)
Viscosity Not available.
Other information
Density 1.23 g/ml
Explosive properties Not explosive.
Molecular formula C20H25NO3S
Molecular weight 359.48
Oxidizing properties Not oxidizing.
The product is stable and non-reactive under normal conditions of use, storage and transport.
Chemical stability
Material is stable under normal conditions.
Possibility of hazardous reactions
No dangerous reaction known under conditions of normal use.
Conditions to avoid
Avoid temperatures exceeding the decomposition temperature. Contact with incompatible
Incompatible materials Strong oxidizing agents.
Hazardous decomposition products
No hazardous decomposition products are known.

TOXICOLOGICAL INFORMATIONInformation on likely routes of exposure
Inhalation No adverse effects due to inhalation are expected.
Skin contact
No adverse effects due to skin contact are expected.
Eye contact
Direct contact with eyes may cause temporary irritation.
Expected to be a low ingestion hazard.
Symptoms related to the physical, chemical and toxicological characteristics
Direct contact with eyes may cause temporary irritation.
Information on toxicological effects
Acute toxicity
Isofetamid (CAS 875915-78-9)
Dermal LD50 Rat > 2000 mg/kg
Inhalation LC50 Rat > 4.8 mg/l
Acute Oral LD50 Rat > 2000 mg/kg
Skin corrosion/irritation
Prolonged skin contact may cause temporary irritation.
Serious eye damage/eye irritation
Direct contact with eyes may cause temporary irritation.
Respiratory or skin sensitization
Respiratory sensitization
Not a respiratory sensitizer.
Skin sensitization
This product is not expected to cause skin sensitization.
No data available to indicate product or any components present at greater than 0.1% are
mutagenic or genotoxic.
Germ cell mutagenicity
No data available to indicate product or any components present at greater than 0.1% are
mutagenic or genotoxic.
This product is not considered to be a carcinogen by IARC, ACGIH, NTP, or OSHA.
IARC Monographs. Overall Evaluation of Carcinogenicity
Not available.
US. National Toxicology Program (NTP) Report on Carcinogens
Not available.
US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050)
Not listed.
Reproductive toxicity
This product is not expected to cause reproductive or developmental effects.
Specific target organ toxicity - single exposure
Not classified.
Specific target organ toxicity - repeated exposure
Not classified.
Aspiration hazard Not an aspiration hazard
ECOLOGICAL INFORMATIONEcotoxicity Toxic to aquatic life with long lasting effects.
Isofetamid (CAS 875915-78-9)
Fish LC50 Oncorhynchus mykiss 2.27 mg/l, 96 hours
Persistence and degradability
No data is available on the degradability of this product.
Bioaccumulative potential No data available.
Mobility in soil No data available.
Other adverse effects
No other adverse environmental effects (e.g. ozone depletion, photochemical ozone creation
potential, endocrine disruption, global warming potential) are expected from this component.
Collect and reclaim or dispose in sealed containers at licensed waste disposal site. Do not allow
this material to drain into sewers/water supplies. Do not contaminate ponds, waterways or ditches
with chemical or used container. Dispose of contents/container in accordance with
local/regional/national/international regulations.
Local disposal regulations
Dispose in accordance with all applicable regulations.
Hazardous waste code
The waste code should be assigned in discussion between the user, the producer and the waste
disposal company.
Waste from residues / unused products
Dispose of in accordance with local regulations. Empty containers or liners may retain some
product residues. This material and its container must be disposed of in a safe manner (see:
Disposal instructions).
Contaminated packaging
Since emptied containers may retain product residue, follow label warnings even after container is
emptied. Empty containers should be taken to an approved waste handling site for recycling or
UN number UN3077
UN proper shipping name Environmentally hazardous substances, solid, n.o.s.
Transport hazard class(es)
Class 9
Subsidiary risk -
Label(s) 9
Packing group III
Special precautions for user
Read safety instructions, SDS and emergency procedures before handling.
Special provisions
8, 146, 335, A112, B54, IB8, IP3, N20, T1, TP33
Packaging exceptions 155
Packaging non bulk 213
Packaging bulk 240
UN number UN3077
UN proper shipping name
Environmentally hazardous substance, solid, n.o.s.
Transport hazard class(es)
Class 9
Subsidiary risk -
Packing group III
Environmental hazards No.
ERG Code 9L
Special precautions for user
Read safety instructions, SDS and emergency procedures before handling.
Other information
Passenger and cargo aircraft Allowed.
Cargo aircraft only Allowed.
UN number UN3077
UN proper shipping name
Transport hazard class(es)
Class 9
Subsidiary risk -
Packing group III
Environmental hazards
Marine pollutant No.
EmS F-A, S-F
Special precautions for user
Read safety instructions, SDS and emergency procedures before handling.
Transport in bulk according to Not applicable
Annex II of MARPOL 73/78 and the IBC Code

This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication
Standard, 29 CFR 1910.1200.
One or more components are not listed on TSCA.
TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D)
Not regulated.
CERCLA Hazardous Substance List (40 CFR 302.4)
Not listed.
SARA 304 Emergency release notification
Not regulated.
US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050)
Not listed.
Superfund Amendments and Reauthorization Act of 1986 (SARA)
Hazard categories
Immediate Hazard - No
Delayed Hazard - No
Fire Hazard - No
Pressure Hazard - No
Reactivity Hazard - No
SARA 302 Extremely hazardous substance Not listed.
SARA 311/312 Hazardous chemical No
SARA 313 (TRI reporting) Not regulated.
Other federal regulations
Clean Air Act (CAA) Section 112 Hazardous Air Pollutants (HAPs) List
Not regulated.
Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130)
Not regulated.
Safe Drinking Water Act (SDWA) Not regulated.
US state regulations
US. California Controlled Substances. CA Department of Justice (California Health and Safety Code Section 11100)
Not listed.
US. Massachusetts RTK - Substance List
Not regulated.
US. New Jersey Worker and Community Right-to-Know Act
Not regulated.
US. Pennsylvania RTK - Hazardous Substances
Not regulated.
US. Pennsylvania Worker and Community Right-to-Know Law
Not listed.
US. Rhode Island RTK
Not regulated.
US. California Proposition 65
California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65): This material is not known to contain
any chemicals currently listed as carcinogens or reproductive toxins.
International Inventories
Country(s) or region Inventory name On inventory (yes/no)*
Australia Australian Inventory of Chemical Substances (AICS) No
Canada Domestic Substances List (DSL) No
Canada Non-Domestic Substances List (NDSL) No
China Inventory of Existing Chemical Substances in China (IECSC) No
Europe European Inventory of Existing Commercial Substances (EINECS) Chemical No
Europe European List of Notified Chemical Substances (ELINCS) No
Japan Inventory of Existing and New Chemical Substances (ENCS) No
Korea Existing Chemicals List (ECL) No
New Zealand New Zealand Inventory No
Philippines Philippine Inventory of Chemicals and Chemical Substances (PICCS) No
United States & Puerto Rico Toxic Substances Control Act (TSCA) Inventory No

*A "Yes" indicates that all components of this product comply with the inventory requirements administered by the governing country(s)
A "No" indicates that one or more components of the product are not listed or exempt from listing on the inventory administered by the governing

OTHER INFORMATIONThe above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any
guarantee of the properties of the product. For lab use only!