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2,2'-Thiodiethanol

Item number	687061
CAS	111-48-8
Formula	C4H10O2S
Molecular weight	122,19 g/mol
Quantity	1x1000mg
storage conditions	4 °C
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Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate November 20, 2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	2,2'-Thiodiethanol
Catalog No.:	687061
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards GmbH An der Laakenwiese 7 04838 Jesewitz Deutschland Tel. +49 34241 54 990 Fax. +49 34241 54 9999 contact@hpc-standards.com
Emergency telephone number	HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours.
HAZARDS IDENTIFICATION	2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Eye irritation (Category 2), H319
Label elements
Pictogram	GHS07 exclam exclam
	2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Warning Hazard statement(s) H319 Causes serious eye irritation. Precautionary statement(s) P264 Wash skin thoroughly after handling. P280 Wear eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention. Supplemental Hazard Statements none 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. Stench.
COMPOSITION/INFORMATION ON INGREDIENTS	3.1 Substances Formula : C4H10O2S Molecular weight : 122,19 g/mol CAS-No. : 111-48-8 EC-No. : 203-874-3 Index-No. : 603-081-00-6 Component Classification Concentration Thiodiglycol Eye Irrit. 2; H319 <= 100 %
Formula	C4H10O2S
Molecular Weight (g/mol)	122.19
CAS-No.	111-48-8
FIRST AID MEASURES	4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available
FIRE-FIGHTING MEASURES	5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture Carbon oxides, Sulphur oxides 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information No data available
ACCIDENTAL RELEASE MEASURES	6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. For personal protection see section 8. 6.2 Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13.
HANDLING AND STORAGE	7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. Store in cool place. 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION
PHYSICAL AND CHEMICAL PROPERTIES	9.1 Information on basic physical and chemical properties a) Appearance Form: viscous liquid b) Odour Stench. c) Odour Threshold No data available d) pH No data available e) Melting point/freezing point Melting point/range: 16 °C f) Initial boiling point and boiling range 164 - 166 °C at 27 hPa g) Flash point 113 °C - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits Upper explosion limit: 5,2 %(V) Lower explosion limit: 1,2 %(V) k) Vapour pressure 0,003 hPa at 22,5 °C l) Vapour density No data available m) Relative density 1,221 g/mL at 25 °C n) Water solubility 1.000 g/l at 20 °C o) Partition coefficient: n-octanol/water log Pow: -0,75 p) Auto-ignition temperature 245 °C at 1.013 hPa q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available 9.2 Other safety information No data available
STABILITY AND REACTIVITY	10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid No data available 10.5 Incompatible materials No data available 10.6 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, Sulphur oxides Other decomposition products - No data available In the event of fire: see section 5
TOXICOLOGICAL INFORMATION	11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - 6.610 mg/kg LD50 Dermal - Rabbit - 23.640 mg/kg Skin corrosion/irritation Skin - Rabbit Result: No skin irritation Serious eye damage/eye irritation No data available Respiratory or skin sensitisation Maximisation Test - Guinea pig Did not cause sensitisation on laboratory animals. Germ cell mutagenicity in vitro assay S. typhimurium Result: negative Mutagenicity (micronucleus test) Mouse - male Result: negative Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity No data available Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information Repeated dose toxicity - Rat - male and female - Gavage - No observed adverse effect level - 100 mg/kg RTECS: KM2975000 Nausea, Headache, Vomiting, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated
ECOLOGICAL INFORMATION	12.1 Toxicity Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - > 10.000 mg/l - 96 h Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - > 500 mg/l - 48 h Toxicity to algae static test EC50 - Desmodesmus subspicatus (green algae) - > 500 mg/l - 72 h 12.2 Persistence and degradability Biodegradability 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Other adverse effects No data available
DISPOSAL CONSIDERATIONS	13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself. Contaminated packaging Dispose of as unused product.
TRANSPORT INFORMATION	14.1 UN number ADR/RID: - IMDG: - IATA: 3334 14.2 UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Aviation regulated liquid, n.o.s. (Thiodiglycol) 14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: 9 14.4 Packaging group ADR/RID: - IMDG: - IATA: III 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user No data available
REGULATORY INFORMATION	15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!