Products

1-Benzhydrylpiperazine

Item number	690575
CAS	841-77-0
Formula	C17H20N2
Molecular weight	252,35 g/mol
Quantity	1x100mg
storage conditions	4 °C
CoA / MSDS	Retrieve CoA Retrieve MSDS Show Safety Data Sheet online

Price

Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate July 23, 2026
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	1-Benzhydrylpiperazine
Catalog No.:	690575
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards Inc 271 17th Street, NW, Suite 1750 Atlanta, GA 30363 Tel. +1 (678) 244-1536 Fax. +1 (404) 586-6820 sales@hpc-standards.us
Emergency telephone number	HPC Standards Tel. +1 (678) 244-1536 This number is only available during office hours.
HAZARDS IDENTIFICATION	2.1. Classification of the substance or mixture Regulation (EC) No 1272/2008 Acute toxicity - Oral Category 3 - (H301) Serious eye damage/eye irritation Category 1 - (H318) Skin sensitisation Category 1A - (H317) Reproductive toxicity Category 2 - (H361) Specific target organ toxicity — single exposure Category 1 - (H370) Specific target organ toxicity — repeated exposure Category 1 - (H372) Chronic aquatic toxicity Category 2 - (H411)
Label elements
Pictogram	GHS05 acid acid GHS06 skull skull GHS08 silhouete silhouete GHS09 Aquatic-pollut-red Aquatic-pollut-red
	Contains 1-(Diphenylmethyl)piperazine Signal word Danger Hazard statements H301 - Toxic if swallowed H317 - May cause an allergic skin reaction H318 - Causes serious eye damage H361 - Suspected of damaging fertility or the unborn child H370 - Causes damage to organs H372 - Causes damage to organs through prolonged or repeated exposure H411 - Toxic to aquatic life with long lasting effects Precautionary Statements - EU (§28, 1272/2008) P260 - Do not breathe dust/fume/gas/mist/vapours/spray P273 - Avoid release to the environment P280 - Wear protective gloves/protective clothing/eye protection/face protection P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P391 - Collect spillage 2.3. Other hazards Toxic to aquatic life. This substance does not meet the PBT/vPvB criteria of REACH, annex XIII. This product does not contain any known or suspected endocrine disruptors. Chemical name 1-(Diphenylmethyl)piperazine EU - REACH (1907/2006) - Article 59(1) - Candidate List of Substances of Very High Concern (SVHC) for Authorisation EU - REACH (1907/2006) - Endocrine Disruptor Assessment List of Substances
COMPOSITION/INFORMATION ON INGREDIENTS	Chemical name 1-(Diphenylmethyl)piperazine 841-77-0 Weight-% 100 REACH registration number:- EC No (EU Index No) 212-667-7 Classification according to Regulation (EC) No.1272/2008 [CLP] Acute Tox. 3 (H301) Eye Dam. 1 (H318)Skin Sens. 1A (H317)Repr. 2 (H361)STOT SE 1 (H370)STOT RE 1 (H372)Aquatic Chronic 2(H411) Specific concentrationlimit (SCL):- M-Factor M-Factor (long-term):- Full text of H- and EUH-phrases: see section 16 Acute Toxicity Estimate If LD50/LC50 data is not available or does not correspond to the classification category, then the appropriate conversion value from CLP Annex I, Table 3.1.2, is used to calculate the acute toxicity estimate (ATEmix) for classifying a mixture based on its components Chemical name 1-(Diphenylmethyl)pipera zine 841-77-0 Oral LD50 mg/kg 500 Dermal LD50 mg/kg 2000 Inhalation LC50 - 4 hour - dust/mist - mg/L No data available Inhalation LC50 - 4 hour - vapour - mg/L No data available Inhalation LC50 - 4hour - gas - ppm No data available This product does not contain candidate substances of very high concern at a concentration >=0.1% (Regulation (EC) No. 1907/2006 (REACH), Article 59)
Formula	C17H20N2
Molecular Weight (g/mol)	252.35
CAS-No.	841-77-0
FIRST AID MEASURES	4.1. Description of first aid measures General advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Inhalation Remove to fresh air. Get medical attention immediately if symptoms occur. IF exposed or concerned: Get medical advice/attention. Eye contact Get immediate medical advice/attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Keep eye wide open while rinsing. Do not rub affected area. Skin contact Wash off immediately with soap and plenty of water for at least 15 minutes. May cause an allergic skin reaction. If symptoms persist, call a doctor. Ingestion Do NOT induce vomiting. Rinse mouth. Never give anything by mouth to an unconscious person. Get medical attention. Self-protection of the first aider Avoid contact with skin, eyes or clothing. Wear personal protective clothing (see section 8). 4.2. Most important symptoms and effects, both acute and delayed Symptoms Burning sensation. Itching. Rashes. Hives. 4.3. Indication of any immediate medical attention and special treatment needed Note to doctors May cause sensitisation in susceptible persons. Treat symptomatically.
FIRE-FIGHTING MEASURES	5.1. Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. 5.2. Special hazards arising from the substance or mixture Specific hazards arising from the chemical Product is or contains a sensitiser. May cause sensitisation by skin contact. 5.3. Advice for firefighters Special protective equipment and precautions for fire-fighters Firefighters should wear self-contained breathing apparatus and full firefighting turnout gear. Use personal protection equipment.
ACCIDENTAL RELEASE MEASURES	6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Ensure adequate ventilation. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Other information Refer to protective measures listed in Sections 7 and 8. For emergency responders Use personal protection recommended in Section 8. 6.2. Environmental precautions Environmental precautions Prevent further leakage or spillage if safe to do so. 6.3. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Take up mechanically, placing in appropriate containers for disposal. Prevention of secondary hazards Clean contaminated objects and areas thoroughly observing environmental regulations. 6.4. Reference to other sections Reference to other sections See section 8 for more information. See section 13 for more information.
HANDLING AND STORAGE	7.1. Precautions for safe handling Advice on safe handling Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Ensure adequate ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Take off contaminated clothing and wash it before reuse. Remove contaminated clothing and shoes. General hygiene considerations Wash hands before breaks and immediately after handling the product. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. 7.2. Conditions for safe storage, including any incompatibilities Storage Conditions Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. Store locked up. Please refer to the manufacturers certificate for specific storage and transport temperature conditions. Store only in the original receptacle unless other advice is given on the CoA. 7.3. Specific end use(s) Risk Management Methods (RMM) The information required is contained in this Safety Data Sheet.
EXPOSURE CONTROLS/PERSONAL PROTECTION	8.1. Control parameters Exposure Limits This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Biological occupational exposure limits This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Derived No Effect Level (DNEL) No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Personal protective equipment Eye/face protection Tight sealing safety goggles. Avoid contact with eyes. Wear safety glasses with side shields (or goggles). Hand protection Wear suitable gloves. The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the related standard EN374. Wear protective nitrile rubber gloves. Skin and body protection Wear suitable protective clothing. Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Wash hands before breaks and immediately after handling the product. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye/face protection. Environmental exposure controls Do not allow into any sewer, on the ground or into any body of water.
PHYSICAL AND CHEMICAL PROPERTIES	9.1. Information on basic physical and chemical properties Physical state Solid Appearance Solid Colour white to beige Odour No information available. Odour threshold No information available Property Values Remarks • Method Melting point / freezing point 89 - 92 °C None known Initial boiling point and boiling rangeNo data available None known Flammability No data available None known Flammability Limit in Air None known Upper flammability or explosive limits No data available Lower flammability or explosive limits No data available Flash point No data available None known Autoignition temperature No data available None known Decomposition temperature None known pH No data available None known pH (as aqueous solution) No data available No information available Kinematic viscosity No data available None known Dynamic viscosity No data available None known Water solubility No data available 0.476 g/L None known Solubility(ies) No data available None known Partition coefficient 0.6 None known Vapour pressure 0.001 Pa @20 °C None known Relative density 1.17 None known Bulk density No data available Liquid Density No data available Relative vapour density No data available None known Particle characteristics Particle Size No information available Particle Size Distribution No information available 9.2. Other information Molecular weight 252.35 Molecular formula C17H20N2 9.2.1. Information with regards to physical hazard classes Not applicable 9.2.2. Other safety characteristics No information available
STABILITY AND REACTIVITY	10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Explosion data Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid None known based on information supplied. 10.5. Incompatible materials Incompatible materials Strong acids. Strong bases. Strong oxidising agents. Hazardous decomposition products None known based on information supplied.
TOXICOLOGICAL INFORMATION	11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Eye contact Specific test data for the substance or mixture is not available. Causes serious eye damage. May cause irreversible damage to eyes. Skin contact Specific test data for the substance or mixture is not available. May cause irritation. May cause sensitisation by skin contact. Repeated or prolonged skin contact may cause allergic reactions with susceptible persons. (based on components). Ingestion Specific test data for the substance or mixture is not available. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhoea. Toxic if swallowed. (based on components). Symptoms related to the physical, chemical and toxicological characteristics Symptoms Redness. Burning. May cause blindness. Itching. Rashes. Hives. Numerical measures of toxicity Acute toxicity Component Information 1-(Diphenylmethyl)piperazine Oral LD50 >= 50 - <= 300 mg/kg ( Rat ) Dermal LD50 > 2000 mg/kg ( Rat ) Inhalation LC50 Delayed and immediate effects as well as chronic effects from short and long-term exposure Skin corrosion/irritation May cause skin irritation. Serious eye damage/eye irritation Classification based on data available for ingredients. Causes burns. Causes serious eye damage. Respiratory or skin sensitisation May cause an allergic skin reaction. Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity Contains a known or suspected reproductive toxin. Classification based on data available for ingredients. Suspected of damaging fertility or the unborn child. STOT - single exposure Based on the classification criteria of the Globally Harmonized System as adopted in the country or region with which this safety data sheet complies, this product has been determined to cause systemic target organ toxicity from acute exposure. (STOT SE). Causes damage to organs if swallowed. STOT - repeated exposure Causes damage to organs through prolonged or repeated exposure. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Other adverse effects No information available.
ECOLOGICAL INFORMATION	12.1. Toxicity Ecotoxicity Toxic to aquatic life. Toxic to aquatic life with long lasting effects. Chemical name 1-(Diphenylmethyl)piperazine Algae/aquatic plants EC50: = 1.82 mg/L (72h, Pseudokirchneriellasubcapitata) Fish LC50: = 16 mg/L 96h, Carp) Toxicity to microorganisms:- Crustacea EC50: = 8.1 mg/L (48h,Daphnia magna) 12.2. Persistence and degradability Persistence and degradability No information available. 12.3. Bioaccumulative potential Bioaccumulation There is no data for this product. Component Information Chemical name 1-(Diphenylmethyl)piperazine Partition coefficient 0.6 12.4. Mobility in soil Mobility in soil No information available. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment Chemical name 1-(Diphenylmethyl)piperazine PBT and vPvB assessment The substance is not PBT / vPvB 12.6. Endocrine disrupting properties Endocrine disrupting properties No information available. 12.7. Other adverse effects No information available.
DISPOSAL CONSIDERATIONS	13.1. Waste treatment methods Waste from residues/unused products Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Contaminated packaging Do not reuse empty containers.
TRANSPORT INFORMATION	IATA 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine) 14.3 Transport hazard class(es) 6.1 14.4 Packing group III Description UN2811, Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine), 6.1, III 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions A3, A5 ERG Code 6L IMDG 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine) 14.3 Transport hazard class(es) 6.1 14.4 Packing group III Description UN2811, Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine), 6.1, III, Marine pollutant 14.5 Marine pollutant P Environmental hazards Yes 14.6 Special precautions for user Special Provisions 223, 274 EmS-No F-A, S-A No information available 14.7 Maritime transport in bulk according to IMO instruments No information available RID 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine) 14.3 Transport hazard class(es) 6.1 14.4 Packing group III Description UN2811, Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine), 6.1, III, Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 ADR 14.1 UN number or ID number UN2811 14.2 UN proper shipping name Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine) 14.3 Transport hazard class(es) 6.1 14.4 Packing group III Description UN2811, Toxic solid, organic, n.o.s. (1-(Diphenylmethyl)piperazine), 6.1, III, (E), Environmentally Hazardous 14.5 Environmental hazards Yes 14.6 Special precautions for user Special Provisions 274, 614 Classification code T2 Tunnel restriction code (E)
REGULATORY INFORMATION	15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture Water hazard class (WGK) non-hazardous to water (nwg) Poland SDS created according to the following Polish regulation: Act of February 25, 2011 on chemical substances and their mixtures (Journal of Laws of 2018, item 143, as amended). Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing the European Chemicals Agency (EC) as amended. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, as amended. Regulation of the Minister of Health of 10 August 2012 on the criteria and method of classifying chemical substances and their mixtures (Journal of Laws of 2012, item 1018). Regulation of the Minister of Health of 20 April 2012 on labeling packaging of hazardous substances and mixtures and some mixtures (Journal of Laws of 2012, item 445). Regulation of the Minister of Family, Labor and Social Policy of 12 June 2018 on the maximum allowable concentrations and intensities of factors harmful to health in the work environment (Journal of Laws of 2018, item 1286). Announcement of the Minister of Economy, Labor and Social Policy of August 28, 2003 on the publication of the unified text of the Ordinance of the Minister of Labor and Social Policy on general health and safety at work regulations (Journal of Laws of 2003, No. 169, item 1650) . Regulation of the Minister of Health of 30 December 2004 on occupational safety and health related to the presence of chemical agents in the workplace (Journal of Laws of 2005, No. 11, item 86). Act of December 14, 2012 on waste (Journal of Laws of 2013, item 21) Regulation of the Minister of Health of December 30, 2004 on occupational health and safety related to the presence of chemical agents in the workplace (Journal U. of 2005, No. 11, item 86). Waste Act of December 14, 2012 (Journal of Laws of 2013, item 21). Act of 13 June 2013 on the management of packaging and packaging waste, Journal of Laws 2013, item 888). Government statement of September 24, 2002 - European Agreement on the International Carriage of Dangerous Goods by Road (ADR) (Journal of Laws No. 194, item 1629 and Journal of Laws of 2003, No. 207, item 2013 and 2014). European Union Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorisations and/or restrictions on use: This product does not contain substances subject to authorisation (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product does not contain substances subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) DIRECTIVE (EU) 2021/1187 on the marketing and use of explosives precursors Not applicable Persistent Organic Pollutants Not applicable Dangerous substance category per Seveso Directive (2012/18/EU) H3 - STOT SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE E2 - Hazardous to the Aquatic Environment in Category Chronic 2 Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Not applicable International Inventories TSCA Complies under research and development exemption or is regulated by a different government agency. DSL/NDSL Contact supplier for inventory compliance status EINECS/ELINCS Contact supplier for inventory compliance status ENCS Contact supplier for inventory compliance status IECSC Contact supplier for inventory compliance status KECL Contact supplier for inventory compliance status PICCS Contact supplier for inventory compliance status AIIC Contact supplier for inventory compliance status Legend: TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances AICS - Australian Inventory of Chemical Substances 15.2. Chemical safety assessment Chemical Safety Report A Chemical Safety Assessment is not required for this substance
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!