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17a-Ethinylestradiol
| Item number | 672998 |
| CAS | 57-63-6 |
| Formula | C20H24O2 |
| Molecular weight | 296,40 g/mol |
| Quantity | 1x250mg |
| Storage conditions | 4 °C |
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| Safety Data Sheet | according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate April 18, 2024 |
| IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING | |
| Product name: | 17a-Ethinylestradiol |
| Catalog No.: | 672998 |
| Relevant identified uses of the substance or mixture | Identified: Laboratory chemical uses: R&D |
| Uses advised against: | HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com |
| Emergency telephone number | HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours. |
| HAZARDS IDENTIFICATION | 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Acute toxicity, Oral (Category 4) Carcinogenicity (Category 1B) Classification according to EU Directives 67/548/EEC or 1999/45/EC May cause cancer. Harmful if swallowed |
| Label elements | |
| Pictogram | GHS07 exclam exclam GHS08 silhouete silhouete |
| Signal word Danger Hazard statement(s) H302 Harmful if swallowed. H350 May cause cancer. Precautionary statement(s) P201 Obtain special instructions before use. P308 + P313 IF exposed or concerned: Get medical advice/ attention. Supplemental Hazard Statements none Restricted to professional users According to European Directive 67/548/EEC as amended. Hazard symbol(s) R-phrase(s) R45 May cause cancer. R22 Also harmful if swallowed. S-phrase(s) S53 Avoid exposure - obtain special instructions before use. S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. Restricted to professional users. 2.3 Other hazards - none | |
| COMPOSITION/INFORMATION ON INGREDIENTS | 3.1 Substances Synonyms : 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 19-Nor-1,3,5(10),17α-pregnatrien-20-yne-3,17-diol Ethinylestradiol Formula : C20H24O2 Molecular Weight : 296,4 g/mol Component Concentration 17α-Ethynylestradiol CAS-No. EC-No. 57-63-6 200-342-2 - |
| Formula | C20H24O2 |
| Molecular Weight (g/mol) | 296.40 |
| CAS-No. | 57-63-6 |
| FIRST AID MEASURES | 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 4.2 Most important symptoms and effects, both acute and delayed 4.3 Indication of any immediate medical attention and special treatment needed no data available |
| FIRE-FIGHTING MEASURES | 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide 5.2 Special hazards arising from the substance or mixture Carbon oxides 5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. 5.4 Further information no data available |
| ACCIDENTAL RELEASE MEASURES | 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. 6.3 Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13 |
| HANDLING AND STORAGE | 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special instructions before use. Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. 7.2 Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. 7.3 Specific end use(s) no data available |
| EXPOSURE CONTROLS/PERSONAL PROTECTION | 8.1 Control parameters Components with workplace control parameters 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). |
| PHYSICAL AND CHEMICAL PROPERTIES | 9.1 Information on basic physical and chemical properties a) Appearance Form: solid b) Odour no data available c) Odour Threshold no data available d) pH no data available e) Melting point/freezing point Melting point/range: 182 - 183 °C - lit. f) Initial boiling point and boiling range no data available g) Flash point no data available h) Evaporation rate no data available i) Flammability (solid, gas) no data available j) Upper/lower flammability or explosive limits no data available k) Vapour pressure no data available l) Vapour density no data available m) Relative density no data available n) Water solubility no data available o) Partition coefficient: noctanol/ water no data available p) Auto-ignition temperature no data available q) Decomposition temperature no data available r) Viscosity no data available s) Explosive properties no data available t) Oxidizing properties no data available 9.2 Other safety information no data available |
| STABILITY AND REACTIVITY | 10.1 Reactivity no data available 10.2 Chemical stability no data available 10.3 Possibility of hazardous reactions no data available 10.4 Conditions to avoid no data available 10.5 Incompatible materials Strong oxidizing agents 10.6 Hazardous decomposition products Other decomposition products - no data available |
| TOXICOLOGICAL INFORMATION | 11.1 Information on toxicological effects Acute toxicity LD50 Oral - rat - 960 mg/kg Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available Carcinogenicity There is sufficient evidence for the carcinogenicity of ethinylestradiol in experimental animals. In the absence of adequate data in humans, it is reasonable, for practical purposes to regard ethinylestradiol as if it presented a carcinogenic risk to humans. Studies in humans strongly suggest that the administration of estrogens is causally related to an increased incidence of endometrial carcinoma; there is no evidence that ethinylestradiol is different from other estrogens in this respect. Possible human carcinogen IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity Laboratory experiments have shown teratogenic effects. Overexposure may cause reproductive disorder(s) based on tests with laboratory animals. Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Ingestion Harmful if swallowed. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation. Additional Information RTECS: RC8925000 |
| ECOLOGICAL INFORMATION | 12.1 Toxicity 12.2 Persistence and degradability no data available 12.3 Bioaccumulative potential no data available 12.4 Mobility in soil no data available 12.5 Results of PBT and vPvB assessment no data available 12.6 Other adverse effects Very toxic to aquatic life with long lasting effects. no data available |
| DISPOSAL CONSIDERATIONS | 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product |
| TRANSPORT INFORMATION | 14.1 UN number ADR/RID: 3077 IMDG: 3077 IATA: 3077 14.2 UN proper shipping name ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (17α-Ethynylestradiol) IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (17α-Ethynylestradiol) IATA: Environmentally hazardous substance, solid, n.o.s. (17α-Ethynylestradiol) 14.3 Transport hazard class(es) ADR/RID: 9 IMDG: 9 IATA: 9 14.4 Packaging group ADR/RID: III IMDG: III IATA: III 14.5 Environmental hazards ADR/RID: yes IMDG Marine Pollutant: yes IATA: yes 14.6 Special precautions for user Further information EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous Goods > 5L for liquids or > 5kg for solids |
| REGULATORY INFORMATION | This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture no data available 15.2 Chemical Safety Assessment no data available |
| OTHER INFORMATION | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only! |