Products

1-Methylimidazole

Item number	691686
CAS	616-47-7
Formula	C4H6N2
Molecular weight	82,10 g/mol
Quantity	1x250mg
storage conditions	4 °C
CoA / MSDS	Retrieve CoA Retrieve MSDS Show Safety Data Sheet online

Price	Please log in.
Order

Safety Data Sheet	according to Regulation (EC) No 1907/2006 (REACH) Classifications according to Regulation (EC) No 1272/2008. Printdate October 31, 2025
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name:	1-Methylimidazole
Catalog No.:	691686
Relevant identified uses of the substance or mixture	Identified: Laboratory chemical uses: R&D
Uses advised against:	HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 contact@hpc-standards.com
Emergency telephone number	HPC Standards Tel. +49 34291 3372-36 This number is only available during office hours.
HAZARDS IDENTIFICATION	2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Dermal (Category 3), H311 Skin corrosion (Category 1B), H314
Label elements
Pictogram	GHS05 acid acid GHS06 skull skull
	2.2 Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Danger Hazard statement(s) H302 Harmful if swallowed. H311 Toxic in contact with skin. H314 Causes severe skin burns and eye DamagePrecautionary statement(s) P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Supplemental Hazard Statements none 2.3 Other hazards This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher
COMPOSITION/INFORMATION ON INGREDIENTS	3.1 Substances Formula : C4H6N2 Molecular weight : 82,10 g/mol CAS-No. : 616-47-7 EC-No. : 210-484-7 Index-No. : 613-035-00-7 Hazardous ingredients according to Regulation (EC) No 1272/2008 Component Classification Concentration 1-Methylimidazole CAS-No. EC-No. Index-No. 616-47-7 210-484-7 613-035-00-7 Acute Tox. 4; Acute Tox. 3; Skin Corr. 1B; H302, H311, H314 <= 100 %
Formula	C4H6N2
Molecular Weight (g/mol)	82.10
CAS-No.	616-47-7
FIRST AID MEASURES	4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 4.3 Indication of any immediate medical attention and special treatment needed No data available
FIRE-FIGHTING MEASURES	5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture Vapours may form explosive mixture with air. 5.3 Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary. 5.4 Further information Use water spray to cool unopened containers
ACCIDENTAL RELEASE MEASURES	6.1 Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13
HANDLING AND STORAGE	7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2. 7.2 Conditions for safe storage, including any incompatibilities Handle under nitrogen, protect from moisture. Store under nitrogen. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Hygroscopic. Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
EXPOSURE CONTROLS/PERSONAL PROTECTION
PHYSICAL AND CHEMICAL PROPERTIES	9.1 Information on basic physical and chemical properties a) Appearance Form: liquid, clear Colour: colourless b) Odour No data available c) Odour Threshold No data available d) pH 9,5 - 11,5 at 100 g/l at 20 °C e) Melting point/freezing point Melting point/range: -6 °C f) Initial boiling point and boiling range 198 °C g) Flash point 92 °C - closed cup h) Evaporation rate No data available i) Flammability (solid, gas) No data available j) Upper/lower flammability or explosive limits Upper explosion limit: 15,7 %(V) Lower explosion limit: 2,7 %(V) k) Vapour pressure 0,5 hPa at 20 °C l) Vapour density No data available m) Relative density 1,03 g/mL at 25 °C n) Water solubility soluble o) Partition coefficient: noctanol/ water log Pow: -0,189 at 25 °C p) Auto-ignition temperature 488 °C at 1.013 - 1.019 hPa q) Decomposition temperature No data available r) Viscosity No data available s) Explosive properties No data available t) Oxidizing properties No data available 9.2 Other safety information No data available
STABILITY AND REACTIVITY	10.1 Reactivity No data available 10.2 Chemical stability Stable under recommended storage conditions. 10.3 Possibility of hazardous reactions No data available 10.4 Conditions to avoid Exposure to moisture Heat, flames and sparks. 10.5 Incompatible materials Carbon dioxide (CO2), Strong oxidizing agents 10.6 Hazardous decomposition products Other decomposition products - No data available Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx) In the event of fire: see section 5
TOXICOLOGICAL INFORMATION	11.1 Information on toxicological effects Acute toxicity LD50 Oral - Rat - male and female - 1.144 mg/kg (OECD Test Guideline 401) LD50 Dermal - Rabbit - male and female - 400 - 600 mg/kg (OECD Test Guideline 402) Skin corrosion/irritation Skin - Rabbit Result: Corrosive (OECD Test Guideline 404) Serious eye damage/eye irritation Eyes - Rabbit Result: Corrosive (OECD Test Guideline 405) Respiratory or skin sensitisation No data available Germ cell mutagenicity Chromosome aberration test in vitro Chinese hamster lung cells Result: negative Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity No data available Reproductive toxicity - Rat - male and female - Oral Specific target organ toxicity - single exposure No data available Specific target organ toxicity - repeated exposure No data available Aspiration hazard No data available Additional Information Repeated dose toxicity Rat - male and female - Oral - NOAEL : 30 mg/kg RTECS: NI7000000 burning sensation, Cough, wheezing, laryngitis, Shortness of breath, spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated
ECOLOGICAL INFORMATION	12.1 Toxicity Toxicity to fish static test LC50 - Leuciscus idus (Golden orfe) - > 100 - 215 mg/l - 96 h Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 267,94 mg/l - 48 h Toxicity to algae static test EC50 - Desmodesmus subspicatus (Scenedesmus subspicatus) - 180,7 mg/l - 72 h (OECD Test Guideline 201) 12.2 Persistence and degradability Biodegradability aerobic - Exposure time 28 d Result: 0 - 10 % - Not readily biodegradable. (OECD Test Guideline 301F) 12.3 Bioaccumulative potential No data available 12.4 Mobility in soil No data available 12.5 Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 12.6 Other adverse effects May be harmful to aquatic organisms due to the shift of the pH
DISPOSAL CONSIDERATIONS	13.1 Waste treatment methods Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product.
TRANSPORT INFORMATION	14.1 UN number ADR/RID: 3267 IMDG: 3267 IATA: 3267 14.2 UN proper shipping name ADR/RID: CORROSIVE LIQUID, BASIC, ORGANIC, N.O.S. (1-Methylimidazole) IMDG: CORROSIVE LIQUID, BASIC, ORGANIC, N.O.S. (1-Methylimidazole) IATA: Corrosive liquid, basic, organic, n.o.s. (1-Methylimidazole) 14.3 Transport hazard class(es) ADR/RID: 8 IMDG: 8 IATA: 8 14.4 Packaging group ADR/RID: II IMDG: II IATA: II 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user No data available
REGULATORY INFORMATION	15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. National legislation Water contaminating class (Germany): WGK 1, slightly water endangering - ID-Number 2.948 - Classification according to appendix 3 15.2 Chemical safety assessment For this product a chemical safety assessment was not carried out
OTHER INFORMATION	The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. For lab use only!